Welcome to the Fowell Lab
at Cornell University
Understanding how tissue micro-environments shape immune function in infectious and inflammatory disease.
We are actively engaged in defining the signals that enable effector T cells to ‘find’ areas of infection and damage within inflamed tissues. We utilize intravital multiphoton microscopy and optogenetic tools to visualize and manipulate effector CD4+ T cells in situ.
These approaches have revealed extrinsic control of effector CD4+ T cell movement; with roles for chemokines in regulating accumulation and activation at inflamed sites, and roles for T cell integrins in promoting interactions with the extracellular matrix for guided movement. Intrinsic programming of effector CD4+ T cell subsets sets distinct thresholds for sensitivity to these extrinsic cues. By identifying key parameters for T cell effector activity in the inflamed dermis we aim to inform new inflammation-specific therapies.
We are actively seeking postdocs interested in studying the mechanisms of CD4 effector function, with open positions in Immunology, Bioinformatics, Computational biology, or In vivo imaging. See our Academic Jobs Online posting here.
We had our first annual Cookie Exchange in lab to celebrate the past year of research. Happy Holidays!
Congratulations to Marinel Ocasio-Rivera for completing her rotation project! This was her first rotation in BBS, and we wish her the best for her future placements.
Welcome Daniel Netti, a new technician in the lab.
Congratulations to Tiago Zilch for winning an AAI/NYIC Young Investigator Award! He received the award for his research presented at NYIC.
The lab visited Cooperstown, New York for the 24th Annual Upstate New York Immunology Conference (NYIC). Tiago Zilch was selected for a poster talk, and Anastasia Rup and Evan Carter jointly presented a poster.
Welcome Pamela Perez, our newest undergraduate student researcher.
The lab attended the Cornell Immunogenomics Symposium hosted by the Center for Immunology, the Center for Vertebrate Genomics, and the Provost's Genome Biology Task Force. We enjoyed a number of talks from leading researchers in genomic immunology, gene editing, gut microbiome studies, and bioinformatics. Evan Carter and Anastasia Rup jointly presented a poster.
Thanks to all the students, staff, and faculty who came to the lab's Sushi Social, our take on the biweekly TGIF event held in the Department of Microbiology & Immunology. It was a nice afternoon of socializing and rest to start the weekend.
The lab attended the 21st Annual Biomedical & Biological Sciences (BBS) Symposium in the College of Veterinary Medicine, organized in part by our very own Tiago Zilch. Noor Bala, Alex McGurk, Anastasia Rup, Evan Carter, and Tiago exhibited posters at the end of the day, where first-year PhD students had the chance to sample research done in the BBS program.
We had a celebratory lunch outing in Collegetown for Lwiza AitDowd and Nuzat Zaman, our undergraduate researchers. Congratulations and thank you for your hard work this summer!
The lab attended the CCFI/CIHMID Research Symposium at Cornell University, where our undergraduates Lwiza AitDowd and Nuzat Zaman presented posters on their summer research projects. Anastasia Rup and Evan Carter also presented during the poster session.
Congratulations to Tiago Zilch, now PhD Candidate, for passing your A-exam!
Noor Bala and Dr. Fowell both gave talks at Chemotactic Cytokines, a Gordon Research Conference (GRC) held in Les Diablerets, Switzerland.
The lab flew out to Portland, Oregon for IMMUNOLOGY2022, the annual meeting organized by AAI. Noor Bala and Tiago Zilch both presented posters. Noor also gave a podium presentation on her research during the Lymphocyte Homeostasis and Regulation symposium.
Dr. Fowell gave the first talk of the 2nd Intercampus Immunology Symposium held at Cornell Tech in New York City, where Tiago Zilch, Anastasia Rup, and Evan Carter presented posters. The meeting brought together researchers from the Cornell Ithaca campus and Weill Cornell Medicine to establish collaborations and share their work on imaging, tissue immunity, immunogenomics, and the microbiome.
The lab attended the 2022 CIHMID/CCFI Research Symposium on campus at Cornell University, where Alex McGurk and Tiago Zilch presented posters, and we heard a number of great talks from trainees and faculty.
Congratulations to Lwiza AitDowd and Nuzat Zaman for their acceptance into the CIHMID Undergraduate Research Experience Program!
Congratulations Noor Bala for winning an AAI Trainee Abstract Award! Her abstract has been selected for oral presentation in Block Symposia at IMMUNOLOGY2022, hosted by The American Association of Immunologists.
Welcome Lwiza AitDowd, Shiveen Kumar, and Nuzat Zaman, our new undergraduate student researchers!
We had a lovely holiday dinner out to celebrate the end of the year. Thank you to the spouses and partners in attendance, it was wonderful to meet and catch up with you all.
Check out the lab’s recent review on T cell activation niches for Immunological Reviews.
Congrats Noor Bala for winning an AAI NYIC Young Investigator Award! She received the award after giving her poster talk at NYIC in Cooperstown, New York.
Lab off to the 23rd Annual Upstate New York Immunology Conference (NYIC) – Cooperstown here we come.
Welcome Anastasia Rup, Technician, to the lab!
Congrats Noor Bala on passing your A exam. Awesome job!
Check out Dr. Fowell’s review on spatio-temporal control of effector T cell migration.
Farewell Alex Iankoulska. Good luck in grad school!
Welcome Tiago Zilch to the lab as a new grad student from the Biomedical & Biological Sciences PhD Program.
Welcome Evan Moss Carter, our new Technician, to the lab!
Congratulations Hen Prizant on your new Scientist position in the Oncology Biomarker Development, Cancer Immunotherapy group at Genentech. You’re going to do great things.
The Fowell Lab arrives at Cornell. Thanks to the grad students who came with me on this journey, Noor Bala and Alex McGurk. Huge thanks to Scott Leddon, Senior Research Associate for making this move possible and for setting up the lab.